Differential expression, function and response to inflammatory stimuli of 11β-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation

Stromal cells such as fibroblasts play an important role in defining tissue-specific responses during the resolution of inflammation. We hypothesized that this involves tissue-specific regulation of glucocorticoids, mediated via differential regulation of the enzyme 11β-hydroxysteroid dehydrogenase...

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Main Authors: Hardy, Rowan S, Filer, Andrew, Cooper, Mark S, Parsonage, Greg, Raza, Karim, Hardie, Debbie L, Rabbitt, Elizabeth H, Stewart, Paul M, Buckley, Christopher D, Hewison, Martin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779419/
https://ncbi.nlm.nih.gov/pubmed/16846535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1993
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