Prostaglandin E2 synthesis in cartilage explants under compression: mPGES-1 is a mechanosensitive gene

Knee osteoarthritis (OA) results, at least in part, from overloading and inflammation leading to cartilage degradation. Prostaglandin E2 (PGE(2)) is one of the main catabolic factors involved in OA. Its synthesis is the result of cyclooxygenase (COX) and prostaglandin E synthase (PGES) activities wh...

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Main Authors: Gosset, Marjolaine, Berenbaum, Francis, Levy, Arlette, Pigenet, Audrey, Thirion, Sylvie, Saffar, Jean-Louis, Jacques, Claire
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2006
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779392/
https://ncbi.nlm.nih.gov/pubmed/16872525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2024
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