A cell-cycle independent role for p21 in regulating synovial fibroblast migration in rheumatoid arthritis

Rheumatoid arthritis (RA) is characterized by synovial hyperplasia and destruction of cartilage and bone. The fibroblast-like synoviocyte (FLS) population is central to the development of pannus by migrating into cartilage and bone. We demonstrated previously that expression of the cell cycle inhibi...

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Autori principali: Woods, James M, Klosowska, Karolina, Spoden, Darrin J, Stumbo, Nataliya G, Paige, Douglas J, Scatizzi, John C, Volin, Michael V, Rao, Malathi S, Perlman, Harris
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2006
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779389/
https://ncbi.nlm.nih.gov/pubmed/16846525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1999
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