Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by destruction of bone and cartilage, which is mediated, in part, by synovial fibroblasts. Matrix metalloproteinases (MMPs) are a large family of proteolytic enzymes responsible for matrix degradation. Macrophage migration inh...

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Bibliographic Details
Main Authors: Pakozdi, Angela, Amin, Mohammad A, Haas, Christian S, Martinez, Rita J, Haines, G Kenneth, Santos, Lanie L, Morand, Eric F, David, John R, Koch, Alisa E
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779381/
https://ncbi.nlm.nih.gov/pubmed/16872482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2021
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