The drug-binding activity of the multidrug-responding transcriptional regulator BmrR resides in its C-terminal domain.

Rhodamine and tetraphenylphosphonium, the substrates of the Bacillus subtilis multidrug efflux transporter Bmr, induce the expression of Bmr through direct interaction with its transcriptional activator BmrR. Here we show that the C-terminal domain of BmrR, expressed individually, binds both these c...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Markham, P N, Ahmed, M, Neyfakh, A A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177825/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8631728/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.5.1473-1475.1996
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