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The effects of hepatic and renal damage on paracetamol metabolism and excretion following overdosage: A pharmacokinetic study

1. The kinetics of paracetamol metabolism and excretion were studied in 41 patients following overdosage. Acute hepatic necrosis developed in 23 patients and in 3 of these acute renal failure also occurred. Two patients died in hepatic failure. 2. Paracetamol metabolism was impaired in the patients...

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Detalhes bibliográficos
Main Authors: Prescott, L. F., Wright, N.
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1776613/
https://ncbi.nlm.nih.gov/pubmed/4788034
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