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The effects of a new α- and β-adrenoceptor antagonist (AH5158) upon the general and coronary haemodynamics of intact dogs

AH5158, a salicylamide derivative, said to be a blocker of α- and β-adrenoceptors, has been studied in intact anaesthetized dogs. At a dose of 2·5 mg/kg intravenously, the drug increased cardiac output and caused a late fall in mean systemic and pulmonary arterial pressure. Coronary sinus flow incre...

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Detalhes bibliográficos
Autor principal: Maxwell, G. M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1776391/
https://ncbi.nlm.nih.gov/pubmed/4152254
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