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Morphine analgesia, tolerance and physical dependence in the adrenalectomized rat
1. Adrenalectomy reduced the median antinociceptive dose (AD50) of morphine in male Sprague-Dawley rats. The antinociceptive effect was assessed by the tail-flick method of D'Amour & Smith (1941). 2. Tolerance to the antinociceptive effect of morphine developed in adrenalectomized and sham-...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1973
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1776073/ https://ncbi.nlm.nih.gov/pubmed/4737428 |
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