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Effects of clonidine and guanethidine on peripheral sympathetic nerve function in the pithed rat

Clonidine, in low intravenous doses, inhibited the increased heart rate of pithed rats caused by peripheral sympathetic nerve stimulation. The magnitude of this effect was greatest at low frequencies of nerve stimulation, responses to high frequencies being little affected by the drug. In contrast,...

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Bibliographic Details
Main Authors: Armstrong, J. M., Boura, A. L. A.
Format: Artigo
Language:Inglês
Published: 1973
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1776069/
https://ncbi.nlm.nih.gov/pubmed/4723805
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