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Pseudomonas aeruginosa sodA and sodB mutants defective in manganese- and iron-cofactored superoxide dismutase activity demonstrate the importance of the iron-cofactored form in aerobic metabolism.

The consumption of molecular oxygen by Pseudomonas aeruginosa can lead to the production of reduced oxygen species, including superoxide, hydrogen peroxide, and the hydroxyl radical. As a first line of defense against potentially toxic levels of endogenous superoxide, P. aeruginosa possesses an iron...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Hassett, D J, Schweizer, H P, Ohman, D E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177481/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7592406/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.22.6330-6337.1995
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