Opposing effects of oestradiol and progesterone on intracellular pathways and activation processes in the oxidative stress induced activation of cultured rat hepatic stellate cells

Background: Oxidative stress, including the generation of reactive oxygen species (ROS), is involved in hepatofibrogenesis. The authors’ previous studies have shown that oestradiol suppresses hepatic fibrosis in animal models and attenuates the activation of cultured rat hepatic stellate cells (HSCs...

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Detalhes bibliográficos
Main Authors: Itagaki, T, Shimizu, I, Cheng, X, Yuan, Y, Oshio, A, Tamaki, K, Fukuno, H, Honda, H, Okamura, Y, Ito, S
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by Gut 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774809/
https://ncbi.nlm.nih.gov/pubmed/16284289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.053278
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