Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients

Background and aims: Glucagon-like peptide 2 (GLP-2) may improve intestinal absorption in short bowel syndrome (SBS) patients with an end jejunostomy. Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant GLP-2 analogue, prolongs the intestinotrophic properties of GLP-2 in animal models. The s...

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Autors principals: Jeppesen, P B, Sanguinetti, E L, Buchman, A, Howard, L, Scolapio, J S, Ziegler, T R, Gregory, J, Tappenden, K A, Holst, J, Mortensen, P B
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2005 by Gut 2005
Matèries:
Small Intestine
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774653/
https://ncbi.nlm.nih.gov/pubmed/16099790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.061440
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