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Response to interferon alfa is hepatitis B virus genotype dependent: genotype A is more sensitive to interferon than genotype D

Background an aims: Current interferon alfa (IFN) treatment of chronic hepatitis B has limited efficacy. The role of hepatitis B virus (HBV) genotypes for response to IFN was investigated. Patients and methods: HBV genotype was determined by direct sequencing of the HBV X gene in 165 consecutive pat...

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Détails bibliographiques
Auteurs principaux: Erhardt, A, Blondin, D, Hauck, K, Sagir, A, Kohnle, T, Heintges, T, Häussinger, D
Format: Artigo
Langue:Inglês
Publié: Copyright 2005 by Gut 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774609/
https://ncbi.nlm.nih.gov/pubmed/15951551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.060327
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