Thalidomide in the treatment of cancer cachexia: a randomised placebo controlled trial

Background: Proinflammatory cytokines, especially tumour necrosis factor α (TNF-α), play a prominent role in the pathogenesis of cancer cachexia. Thalidomide, which is an inhibitor of TNF-α synthesis, may represent a novel and rational approach to the treatment of cancer cachexia. Aims: To assess th...

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Bibliographic Details
Main Authors: Gordon, J N, Trebble, T M, Ellis, R D, Duncan, H D, Johns, T, Goggin, P M
Format: Artigo
Language:Inglês
Published: Copyright 2005 by Gut 2005
Subjects:
Cancer
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774430/
https://ncbi.nlm.nih.gov/pubmed/15753541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.047563
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