Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: role of viral core and NS5A proteins

Background: Cyclooxygenase 2 (COX-2) and matrix metalloproteinases (MMPs) have been implicated in tissue injury and fibrogenesis in animal models but little is known regarding their role in hepatitis C virus (HCV) related liver disease in humans. Aims: To characterise the intrahepatic expression pat...

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Detalhes bibliográficos
Main Authors: Núñez, O, Fernández-Martínez, A, Majano, P L, Apolinario, A, Gómez-Gonzalo, M, Benedicto, I, López-Cabrera, M, Boscá, L, Clemente, G, García-Monzón, C, Martín-Sanz, P
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2004 by Gut 2004
Assuntos:
Liver
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774290/
https://ncbi.nlm.nih.gov/pubmed/15479690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2003.038364
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