Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn’s disease and ulcerative colitis

Background and aims: Elicitation of an innate immune response to bacterial products is mediated through pattern recognition receptors (PRRs) such as the toll-like receptors (TLRs) and the NODs. The recently characterised Asp299Gly polymorphism in the lipopolysaccharide (LPS) receptor TLR4 is associa...

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Autors principals: Franchimont, D, Vermeire, S, El Housni, H, Pierik, M, Van Steen, K, Gustot, T, Quertinmont, E, Abramowicz, M, Van Gossum, A, Devière, J, Rutgeerts, P
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2004 by Gut 2004
Matèries:
Inflammatory Bowel Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774122/
https://ncbi.nlm.nih.gov/pubmed/15194649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2003.030205
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