Increased cancer risk in heavy drinkers with the alcohol dehydrogenase 1C*1 allele, possibly due to salivary acetaldehyde

Background: Chronic ethanol consumption is associated with an increased risk of upper aerodigestive tract cancer. As acetaldehyde seems to be a carcinogenic factor associated with chronic alcohol consumption, alcoholics with the alcohol dehydrogenase (ADH) 1C*1 allele seem to be particularly at risk...

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Bibliographic Details
Main Authors: Visapää, J P, Götte, K, Benesova, M, Li, J, Homann, N, Conradt, C, Inoue, H, Tisch, M, Hörrmann, K, Väkeväinen, S, Salaspuro, M, Seitz, H K
Format: Artigo
Language:Inglês
Published: Copyright 2004 by Gut 2004
Subjects:
Liver
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774061/
https://ncbi.nlm.nih.gov/pubmed/15138216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2003.018994
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