Fatigue and primary biliary cirrhosis: association of globus pallidus magnetisation transfer ratio measurements with fatigue severity and blood manganese levels

Background and aim: Fatigue is the commonest symptom in primary biliary cirrhosis (PBC), affecting individuals at all stages of disease. The pathogenesis of fatigue in PBC is unknown although rat models suggest a central nervous system (CNS) cause. We examined the hypothesis that a CNS abnormality r...

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Detalhes bibliográficos
Main Authors: Forton, D M, Patel, N, Prince, M, Oatridge, A, Hamilton, G, Goldblatt, J, Allsop, J M, Hajnal, J V, Thomas, H C, Bassendine, M, Jones, D E J, Taylor-Robinson, S D
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2004 by Gut 2004
Assuntos:
Liver
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774014/
https://ncbi.nlm.nih.gov/pubmed/15016756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2003.016766
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