Antibiotics with a selective aerobic or anaerobic spectrum have different therapeutic activities in various regions of the colon in interleukin 10 gene deficient mice

Background and aims: Multiple rodent models implicate resident intestinal bacteria in the pathogenesis of chronic immune mediated intestinal inflammation. Specific pathogen free (SPF) interleukin 10 gene deficient (IL-10(−/−)) mice develop colitis, which does not occur in the germ free (GF) state. W...

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Hauptverfasser: Hoentjen, F, Harmsen, H J M, Braat, H, Torrice, C D, Mann, B A, Sartor, R B, Dieleman, L A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Copyright 2003 by Gut 2003
Schlagworte:
Inflammatory Bowel Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773908/
https://ncbi.nlm.nih.gov/pubmed/14633949
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