Bilirubin inhibits bile acid induced apoptosis in rat hepatocytes

Background and aims: Hydrophobic bile acids contribute to hepatocellular injury in cholestasis and rapidly induce apoptosis in vitro; however, unlike Fas agonists, cholestasis does not cause extensive hepatocyte apoptosis. As antioxidants provide protection against bile acid induced liver injury, ou...

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Bibliographic Details
Main Authors: Granato, A, Gores, G, Vilei, M T, Tolando, R, Ferraresso, C, Muraca, M
Format: Artigo
Language:Inglês
Published: Copyright 2003 by Gut 2003
Subjects:
Liver
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773880/
https://ncbi.nlm.nih.gov/pubmed/14633961
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