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Gastrointestinal safety of AZD3582, a cyclooxygenase inhibiting nitric oxide donator: proof of concept study in humans

Background: Cyclooxygenase inhibiting nitric oxide donators (CINODs) are a new class of anti-inflammatory and analgesic drugs that may minimise gastrointestinal toxicity compared with standard non-steroidal anti-inflammatory drugs (NSAIDs) by virtue of nitric oxide donation. Methods: A proof of conc...

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Detalhes bibliográficos
Main Authors: Hawkey, C J, Jones, J I, Atherton, C T, Skelly, M M, Bebb, J R, Fagerholm, U, Jonzon, B, Karlsson, P, Bjarnason, I T
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2003 by Gut 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773862/
https://ncbi.nlm.nih.gov/pubmed/14570719
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