Activated platelets are the source of elevated levels of soluble CD40 ligand in the circulation of inflammatory bowel disease patients

Background: The CD40/CD40L system, a key regulator and amplifier of immune reactivity, is activated in inflammatory bowel disease (IBD) mucosa. Aims: To determine whether plasma levels of sCD40L are elevated in Crohn’s disease (CD) and ulcerative colitis (UC) patients compared with normal controls,...

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Hauptverfasser: Danese, S, Katz, J A, Saibeni, S, Papa, A, Gasbarrini, A, Vecchi, M, Fiocchi, C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Copyright 2003 by Gut 2003
Schlagworte:
Inflammation and Inflammatory Bowel Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773814/
https://ncbi.nlm.nih.gov/pubmed/12970136
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