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Antagonism of ghrelin receptor reduces food intake and body weight gain in mice

Background and aims: Ghrelin, an endogenous ligand for growth hormone secretagogue receptor (GHS-R), is an appetite stimulatory signal from the stomach with structural resemblance to motilin. We examined the effects of the gastric peptide ghrelin and GHS-R antagonists on energy balance and glycaemic...

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Autors principals: Asakawa, A, Inui, A, Kaga, T, Katsuura, G, Fujimiya, M, Fujino, M A, Kasuga, M
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2003 by Gut 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773718/
https://ncbi.nlm.nih.gov/pubmed/12801949
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