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Incidence of gastroduodenal ulcers in patients with rheumatoid arthritis after 12 weeks of rofecoxib, naproxen, or placebo: a multicentre, randomised, double blind study

Background: Previous studies in patients with osteoarthritis have suggested that the selective cyclooxygenase (COX)-2 inhibitor rofecoxib results in less gastrointestinal damage than non-selective non-steroidal antiinflammatory drugs (NSAIDs). This study compared the incidence of endoscopically dete...

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Autori principali: Hawkey, C J, Laine, L, Simon, T, Quan, H, Shingo, S, Evans, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Group 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773685/
https://ncbi.nlm.nih.gov/pubmed/12740337
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