Transcriptional regulation of the lactase-phlorizin hydrolase gene by polymorphisms associated with adult-type hypolactasia

Background and aims: The mechanism of the developmental downregulation of the lactase-phlorizin hydrolase (LPH) gene underlying adult-type hypolactasia is unknown. We have determined the functional significance of the recently identified two single nucleotide polymorphisms (SNPs), C/T(−13910) and G/...

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Main Authors: Kuokkanen, M, Enattah, N S, Oksanen, A, Savilahti, E, Orpana, A, Järvelä, I
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2003 by Gut 2003
Assuntos:
Small Intestine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773659/
https://ncbi.nlm.nih.gov/pubmed/12692047
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