Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways

Background and aims: Short chain fatty acids (SCFA) exert profound effects on the colonic mucosa. In particular, SCFA modulate mucosal immune functions. The antimicrobial cathelicidin LL-37 is expressed by colon epithelial cells. In the present study the effect of SCFA on LL-37 expression was invest...

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Detalhes bibliográficos
Main Authors: Schauber, J, Svanholm, C, Termén, S, Iffland, K, Menzel, T, Scheppach, W, Melcher, R, Agerberth, B, Lührs, H, Gudmundsson, G H
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2003 by Gut 2003
Assuntos:
Colon
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773650/
https://ncbi.nlm.nih.gov/pubmed/12692061
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