Promoter methylation of E-cadherin gene in gastric mucosa associated with Helicobacter pylori infection and in gastric cancer

Background:E-cadherin is an adhesion molecule involved in tumour invasion/metastasis. Silencing of E-cadherin by promoter CpG methylation has been shown in both familial and sporadic gastric cancers. Helicobacter pylori is a class I carcinogen in gastric cancer. Aims: This study was undertaken to in...

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Autori principali: Chan, A O-O, Lam, S-K, Wong, B C-Y, Wong, W-M, Yuen, M-F, Yeung, Y-H, Hui, W-M, Rashid, A, Kwong, Y-L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright 2003 by Gut 2003
Soggetti:
Helicobacter Pylori
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773595/
https://ncbi.nlm.nih.gov/pubmed/12631658
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