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ICAM-1 and VCAM-1 antisense oligonucleotides attenuate in vivo leucocyte adherence and inflammation in rat inflammatory bowel disease

Background: Recruitment of circulating cells to the inflamed intestine is modulated by adhesion molecules expressed on the surface of both leucocytes and endothelial cells. Aims: The objective of this study was to test whether 2`-O-methoxyethyl chimeric antisense oligonucleotides directed against en...

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Detalhes bibliográficos
Main Authors: Rijcken, E, Krieglstein, C F, Anthoni, C, Laukoetter, M G, Mennigen, R, Spiegel, H U, Senninger, N, Bennett, C F, Schuermann, G
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2002 by Gut 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773394/
https://ncbi.nlm.nih.gov/pubmed/12235075
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