Association between severity of type A hepatitis and nucleotide variations in the 5` non-translated region of hepatitis A virus RNA: strains from fulminant hepatitis have fewer nucleotide substitutions

Background: Type A hepatitis is still a considerable problem in both underdeveloped and developed countries. Why some patients progress to fulminant type A hepatitis and others do not is unclear. Aims: To determine if nucleotide differences in the genome of hepatitis A virus (HAV) are responsible fo...

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Detalhes bibliográficos
Main Authors: Fujiwara, K, Yokosuka, O, Ehata, T, Saisho, H, Saotome, N, Suzuki, K, Okita, K, Kiyosawa, K, Omata, M
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2002 by Gut 2002
Assuntos:
Liver and Biliary Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773280/
https://ncbi.nlm.nih.gov/pubmed/12077097
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