Frequent loss of SMAD4/DPC4 protein in colorectal cancers

Background and aims: Loss of DNA sequences from chromosome 18q21 is a major genetic change in colorectal tumorigenesis. Multiple genes have been identified in this area. One of these, DPC4 (deleted in pancreatic cancer 4, also known as SMAD4), is mutated in a minor subset of colorectal carcinomas as...

Full description

Saved in:

Bibliographic Details
Main Authors:	Salovaara, R, Roth, S, Loukola, A, Launonen, V, Sistonen, P, Avizienyte, E, Kristo, P, Järvinen, H, Souchelnytskyi, S, Sarlomo-Rikala, M, Aaltonen, L A
Format:	Artigo
Language:	Inglês
Published:	Copyright 2002 by Gut 2002
Subjects:	Colorectal Cancer
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1773263/ https://ncbi.nlm.nih.gov/pubmed/12077092
Tags:	Add Tag No Tags, Be the first to tag this record!

Frequent loss of SMAD4/DPC4 protein in colorectal cancers

Similar Items