Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: blocking interleukin 18 attenuates intestinal damage

Background and aims: Persistent inflammation observed in inflammatory bowel disease may be the consequence of an increased or aberrant immune response to normal gut constituents or an overall immune dysregulation and imbalance. Cytokines play an important role in immune regulation and interleukin 18...

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Hauptverfasser: Sivakumar, P V, Westrich, G M, Kanaly, S, Garka, K, Born, T L, Derry, J M J, Viney, J L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Copyright 2002 by Gut 2002
Schlagworte:
Inflammation and Inflammatory Bowel Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773244/
https://ncbi.nlm.nih.gov/pubmed/12010883
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