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Molecular dynamics simulations of unfolding and refolding of a β-hairpin fragment of protein G

We have studied the unfolding and refolding pathway of a β-hairpin fragment of protein G by using molecular dynamics. Although this fragment is small, it possesses several of the qualities ascribed to small proteins: cooperatively formed β-sheet secondary structure and a hydrophobic “core” of packed...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Pande, Vijay S., Rokhsar, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17732/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10430895/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.16.9062
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