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Molecular dynamics simulations of unfolding and refolding of a β-hairpin fragment of protein G

We have studied the unfolding and refolding pathway of a β-hairpin fragment of protein G by using molecular dynamics. Although this fragment is small, it possesses several of the qualities ascribed to small proteins: cooperatively formed β-sheet secondary structure and a hydrophobic “core” of packed...

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Autori principali: Pande, Vijay S., Rokhsar, Daniel S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC17732/
https://ncbi.nlm.nih.gov/pubmed/10430895
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