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Denatured H-ferritin subunit is a major constituent of haemosiderin in the liver of patients with iron overload

Background and aims: Iron is stored in hepatocytes in the form of ferritin and haemosiderin. There is a marked increase in iron rich haemosiderin in iron overloaded livers, and ferric iron in amounts exceeding the ferritin and haemosiderin binding capacity may promote free radical generation, causin...

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Autors principals: Miyazaki, E, Kato, J, Kobune, M, Okumura, K, Sasaki, K, Shintani, N, Arosio, P, Niitsu, Y
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2002 by Gut 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773135/
https://ncbi.nlm.nih.gov/pubmed/11839724
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