Interleukin 18 and associated markers of T helper cell type 1 activity in coeliac disease

Background: Coeliac disease (CD) is caused by a T helper cell type 1 (Th1) response in the small intestinal mucosa to dietary gluten. Paradoxically, interleukin (IL)-12, the major Th1 inducing factor, is undetectable in the mucosa of active CD. IL-18 is a recently described cytokine capable of promo...

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Autores principales: Salvati, V M, MacDonald, T T, Bajaj-Elliott, M, Borrelli, M, Staiano, A, Auricchio, S, Troncone, R, Monteleone, G
Formato: Artigo
Lenguaje:Inglês
Publicado: Copyright 2002 by Gut 2002
Materias:
Coeliac Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773110/
https://ncbi.nlm.nih.gov/pubmed/11788557
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