Generation of transgenic mice with mild and severe retinal neovascularisation

Aim: To generate a mouse model for slow progressive retinal neovascularisation through vascular endothelial growth factor (VEGF) upregulation. Methods: Transgenic mice were generated via microinjection of a DNA construct containing the human VEGF(165) (hVEGF) gene driven by a truncated mouse rhodops...

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Detalhes bibliográficos
Main Authors: Lai, C-M, Dunlop, S A, May, L A, Gorbatov, M, Brankov, M, Shen, W-Y, Binz, N, Lai, Y KY, Graham, C E, Barry, C J, Constable, I J, Beazley, L D, Rakoczy, E P
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 British Journal of Ophthalmology 2005
Assuntos:
Laboratory Science - Extended Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1772733/
https://ncbi.nlm.nih.gov/pubmed/15965177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bjo.2004.059089
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