The relation between c-myc expression and interferon sensitivity in uveal melanoma

Background/aim: Interferons (IFN) are currently being used to treat melanoma, including some patients with uveal melanoma. IFN is thought to inhibit tumour growth through downregulation of the c-myc oncogene; the overexpression of which has been shown to be associated with resistance in cell lines....

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Main Authors: Tulley, P N, Neale, M, Jackson, D, Chana, J S, Grover, R, Cree, I, Grobbelaar, A O, Wilson, G D
Format: Artigo
Jezik:Inglês
Izdano: Copyright 2004 British Journal of Ophthalmology 2004
Teme:
Clinical Science - Extended Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1772437/
https://ncbi.nlm.nih.gov/pubmed/15548813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bjo.2003.033498
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