Sulfonamide resistance in Neisseria meningitidis as defined by site-directed mutagenesis could have its origin in other species.

Sulfonamide resistance in Neisseria meningitidis is mediated by altered forms of the chromosomal gene for the drug target enzyme dihydropteroate synthase. Sulfonamides have been used for decades both for prophylaxis and the treatment of meningococcal disease, and resistance is common. Two types of r...

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Pubblicato in:	J Bacteriol
Autori principali:	Fermer, C, Kristiansen, B E, Sköld, O, Swedberg, G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177231/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7642493/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.16.4669-4675.1995
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