Indomethacin lowers optic nerve oxygen tension and reduces the effect of carbonic anhydrase inhibition and carbon dioxide breathing

Background/aims: Prostaglandins are important in blood flow regulation. Carbon dioxide (CO(2)) breathing and carbonic anhydrase inhibition increase the oxygen tension in the retina and optic nerve. To study the mechanism of this effect and the role of cyclo-oxygenase in the regulation of optic nerve...

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Main Authors: Pedersen, D B, Eysteinsson, T, Stefánsson, E, Kiilgaard, J F, la Cour, M, Bang, K, Jensen, P K
Format: Artigo
Sprog:Inglês
Udgivet: Copyright 2004 British Journal of Ophthalmology 2004
Fag:
Laboratory Science - Extended Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1772262/
https://ncbi.nlm.nih.gov/pubmed/15258031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bjo.2003.041251
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