Expression of a functional fungal polyketide synthase in the bacterium Streptomyces coelicolor A3(2).

The multifunctional 6-methylsalicylic acid synthase gene from Penicillium patulum was engineered for regulated expression in Streptomyces coelicolor. Production of significant amounts of 6-methylsalicylic acid by the recombinant strain was proven by nuclear magnetic resonance spectroscopy. These res...

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Pubblicato in:	J Bacteriol
Autori principali:	Bedford, D J, Schweizer, E, Hopwood, D A, Khosla, C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177212/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7635840/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.15.4544-4548.1995
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