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Bicyclomycin sensitivity and resistance affect Rho factor-mediated transcription termination in the tna operon of Escherichia coli.

The growth-inhibiting drug bicyclomycin, known to be an inhibitor of Rho factor activity in Escherichia coli, was shown to increase basal level expression of the tryptophanase (tna) operon and to allow growth of a tryptophan auxotroph on indole. The drug also relieved polarity in the trp operon and...

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Détails bibliographiques
Publié dans:J Bacteriol
Auteurs principaux: Yanofsky, C, Horn, V
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177196/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7543478/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.15.4451-4456.1995
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