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Molecular dissection of mutations in the Bacillus subtilis spore photoproduct lyase gene which affect repair of spore DNA damage caused by UV radiation.

In response to UV irradiation, Bacillus subtilis spore DNA accumulates the unique thymine dimer 5-thyminyl-5,6-dihydrothymine, or spore photoproduct (SP). SP is broken down into monomers during spore germination by the product of the spl gene which has been proposed to encode the enzyme SP lyase. Th...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Fajardo-Cavazos, P, Nicholson, W L
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1995
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177190/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7635825/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.15.4402-4409.1995
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