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Overproduction of NlpE, a new outer membrane lipoprotein, suppresses the toxicity of periplasmic LacZ by activation of the Cpx signal transduction pathway.

The LamB-LacZ-PhoA tripartite fusion protein is secreted to the periplasm, where it exerts a toxicity of unknown origin during high-level synthesis in the presence of the inducer maltose, a phenotype referred to as maltose sensitivity. We selected multicopy suppressors of this toxicity that allow gr...

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Bibliografske podrobnosti
izdano v:J Bacteriol
Principais autores: Snyder, W B, Davis, L J, Danese, P N, Cosma, C L, Silhavy, T J
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1995
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177165/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7635808/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.15.4216-4223.1995
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