Ser-127-to-Leu substitution in the DNA gyrase B subunit of Streptococcus pneumoniae is implicated in novobiocin resistance.

We report the cloning of the gyrB gene from Streptococcus pneumoniae 533 that carries the nov-1 allele. The gyrB gene codes for a protein homologous to the gyrase B subunit of archaebacteria and eubacteria. The same amino acid substitution (Ser-127 to Leu) confers novobiocin resistance on four isola...

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Argitaratua izan da:	J Bacteriol
Egile Nagusiak:	Muñoz, R, Bustamante, M, de la Campa, A G
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 1995
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177155/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7608096/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.14.4166-4170.1995
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