Increase of mitochondrial DNA in blood cells of patients with Leber’s hereditary optic neuropathy with 11778 mutation

Aims: To investigate the change of mitochondrial DNA (mtDNA) content in Leber’s hereditary optic neuropathy (LHON) with 11778 mutation. Methods: Mitochondrial DNA content in 27 LHON patients with 11778 mutation, 26 asymptomatic maternal relatives, and 23 normal controls was measured using a competit...

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Detalhes bibliográficos
Main Authors: Yen, M-Y, Chen, C-S, Wang, A-G, Wei, Y-H
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2002 British Journal of Ophthalmology 2002
Assuntos:
Clinical Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1771259/
https://ncbi.nlm.nih.gov/pubmed/12185132
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