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Rapid mutation detection by the Transgenomic wave analyser DHPLC identifies MYOC mutations in patients with ocular hypertension and/or open angle glaucoma

Aims: To rapidly screen Scottish patients with a family history of open angle glaucoma (OAG) or ocular hypertension (OHT) for mutations in the myocilin gene (MYOC) and develop a new rapid screening method for MYOC mutation detection. Methods: All three exons of the MYOC gene were amplified by PCR fr...

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Bibliografiska uppgifter
Huvudupphovsmän: Cobb, C J, Scott, G, Swingler, R J, Wilson, S, Ellis, J, MacEwen, C J, McLean, W H I
Materialtyp: Artigo
Språk:Inglês
Publicerad: Copyright 2002 British Journal of Ophthalmology 2002
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1771000/
https://ncbi.nlm.nih.gov/pubmed/11815346
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