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Protein kinase C inhibition attenuates vascular ET(B )receptor upregulation and decreases brain damage after cerebral ischemia in rat

BACKGROUND: Protein kinase C (PKC) is known to be involved in the pathophysiology of experimental cerebral ischemia. We have previously shown that after transient middle cerebral artery occlusion, there is an upregulation of endothelin receptors in the ipsilateral middle cerebral artery. The present...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Henriksson, Marie, Stenman, Emelie, Vikman, Petter, Edvinsson, Lars
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1770924/
https://ncbi.nlm.nih.gov/pubmed/17212812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-8-7
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