The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export

Spt6 promotes transcription elongation at many genes and functions as a histone H3 chaperone to alter chromatin structure during transcription. We show here that mammalian Spt6 binds Ser2-phosphorylated (Ser2P) RNA polymerase II (RNAPII) through a primitive SH2 domain, which recognizes phosphoserine...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Yoh, Sunnie M., Cho, Helen, Pickle, Loni, Evans, Ronald M., Jones, Katherine A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2007
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1770899/
https://ncbi.nlm.nih.gov/pubmed/17234882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1503107
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars