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Lethal and mutagenic actions of N-methyl-N'-nitro-N-nitrosoguanidine potentiated by oxidized glutathione, a seemingly harmless substance in the cellular environment.

Both the lethal and the mutagenic actions of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) on cells of Streptococcus pneumoniae were greatly potentiated by a component of yeast extract added to the cellular environment. This component was found to be an oxidation product of glutathione, glutathione di...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Kumaresan, K R, Springhorn, S S, Lacks, S A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177078/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7601826/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.13.3641-3646.1995
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