Development of immunoglobulin variable heavy chain gene consensus probes with conjugated 3′ minor groove binder groups for monitoring minimal residual disease in childhood acute lymphoblastic leukaemia

Aims: To develop immunoglobulin heavy chain variable (VH) gene probes that are shorter and more flexible in position for monitoring minimal residual disease (MRD) in childhood leukaemia (ALL), using minor groove binder (MGB) technology. Methods: All VH germline sequences registered in the database w...

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Main Authors: Uchiyama, M, Maesawa, C, Yashima, A, Itabashi, T, Satoh, T, Tarusawa, M, Endo, M, Takahashi, Y, Sasaki, S, Tsuchiya, S, Ishida, Y, Masuda, T
Format: Artigo
Jezik:Inglês
Izdano: Copyright 2003 Journal of Clinical Pathology 2003
Teme:
Short Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1770149/
https://ncbi.nlm.nih.gov/pubmed/14645357
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