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Analysis of Shiga toxin subunit association by using hybrid A polypeptides and site-specific mutagenesis.

Shiga toxin (STX), a bacterial toxin produced by Shigella dysenteriae type 1, is a hexamer composed of five receptor-binding B subunits which encircle an alpha-helix at the carboxyl terminus of the enzymatic A polypeptide. Hybrid toxins constructed by fusing the A polypeptide sequences of STX and Sh...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Jemal, C, Haddad, J E, Begum, D, Jackson, M P
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177002/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7768810/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.11.3128-3132.1995
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